METABOLISM OF IODINE (I$sup 131$) AND FORMATION OF IODINATED SCLEROPROTEIN (GORGONINE) OF THE CORNEOUS SKELETON OF EUNICELLA VERRUCOSA (PALLAS)

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Comparative Biochemistry and Physiology (England) Divided into parts A and B

DOI:https://doi.org/10.1016/0010-406X(60)90032-3· OSTI ID:4770416

Roche, J; Andre, S; Salvatore, G

The presence of gorgonins containing up to 10% iodine in the corneous skeleton of sea-fans (gorgons) has long been known. The formation of iodinated amino acids in these proteins was studied with radioactive iodine (I/sup 131/). Gorgons (Eunicella verrucosa (Pallas), var. typica) immersed in sea water containing tracer-doses of NaI/sup 131/ concentrate iodides with remarkable regularity. The efficiency of this process is such that in 15 days at 18 deg C nearly all the iodides present are fixed by the gorgons. Potassium thiocyanate inhibits this phenomenon reversibly, as in thyroid gland. Radiochromatographic analysis of the proteins of living tissues and of corneous skeleton shows that both contain labeled 3-monoiodo- and 3.5-diiodotyrosine. Formation of iodothyronines has not been observed. The synthesis of the two iodinated amino acids seems to take place only in living iodinated amino acids seems to take place only in living tissue secreting the precursors of gorgonins. The fibers of these do not seem to be halogenated later. The presence of iodotyrosines in gorgonins is probably not bound to an elementary thyroid function, even if these compounds are accompanied by traces of thyroxine and 3,5,3'-triiodothyronine, as shown in previous researches. The role of iodotyrosines of gorgonins seems to be only structural; they are probably permanent constituents of the protein fibers of the corneous skeleton. (auth)

• Research Organization: College de France, Finistere; Stazione Zoologica, Napoli, Italy
• NSA Number: NSA-16-032697
• OSTI ID: 4770416
• Journal Information: Comparative Biochemistry and Physiology (England) Divided into parts A and B, Journal Name: Comparative Biochemistry and Physiology (England) Divided into parts A and B Vol. Vol: 1; ISSN CBCPA
• Country of Publication: Country unknown/Code not available
• Language: French

Related Subjects

AMINO ACIDS
ANIMALS
BIOCHEMISTRY
BIOLOGY AND MEDICINE
CALCIUM COMPOUNDS
CHROMATOGRAPHY
CYANATES
EFFICIENCY
HORMONES
IODINE
IODINE 131
LABELLED COMPOUNDS
METABOLISM
ORGANIC SULFUR COMPOUNDS
POTASSIUM COMPOUNDS
PROTEINS
SEA
SODIUM IODIDES
TEMPERATURE
THYROID
THYROXINE
TISSUES
TRACE AMOUNTS
TRACER TECHNIQUES
WATER