THE EFFECT OF IONIZING RADIATION ON THE ANTITOXIC AND ANTIMICROBIAL IMMUNITY (in Russian)
An attempt was made to clarify the effect of ionizing radiation on the antimlcroblal and the antitoxic immunity of animals after vaccinating them with a still experimental, complex vaccine adsorbed on Al hydroxide. The vaccine contained the antigens of dysentery and typhoid fever bacteria and the anatoxlns of botulin, gas gangrene, and teta nus. The twice vaccinated chinchillas were exposed to a sublethal dose of 600 r of Co/sup 60/ gamma rays during the immunity period, 10 days after the vaccination. It was found that this exposure did not affect the antitoxic immunity. After revaccination, a decrease of the antitoxin content to half of its value was noted in some animals. Irradiation of mice with 450 r of x rays 10 days after the revaccination resulted in a similar reduction of the antimicrobial activity. Thus, previous immunization increased the resistance against harmful radiation effects. (TTT)
- Research Organization:
- S.M. Kirov Military Medical Academy, Leningrad
- NSA Number:
- NSA-16-032862
- OSTI ID:
- 4768300
- Journal Information:
- Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Vol. Vol: 2; Other Information: Orig. Receipt Date: 31-DEC-62
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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