ANTIBIOTIC RESISTANCE AND RADIATION INDUCED MUTATION IN CHONDROCOCCUS COLUMNARIS
Technical Report
·
OSTI ID:4755289
Of several antibiotics tested tetracycline, chlortetracycline, and erythromycin were found to be most effective in preventing growth of Chondrococcus columnaris. Mutation rate in C. columnaris was evaluated by determining the xray induced increase in frequency of organisms resistant to distrycin. A fifteen-fold increase over the spontaneous mutation rate was observed when cells were irradiated with 10 kr, a dose which killed 99% of the cells. Mortality of fish exposed to irradiated organisms and a radiationinduced mutant was similar to mortality of fish infected with control cells. (auth)
- Research Organization:
- General Electric Co. Hanford Atomic Products Operation, Richland, Wash.
- DOE Contract Number:
- AT(45-1)-1350
- NSA Number:
- NSA-17-005769
- OSTI ID:
- 4755289
- Report Number(s):
- HW-SA-2540
- Country of Publication:
- United States
- Language:
- English
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OSTI ID:6402633