EFFECT OF X-IRRADIATION ON THE HEPATIC SYNTHESIS OF FATTY ACIDS AND CHOLESTEROL

Journal Article · Mon Dec 17 04:00:00 EST 1962 · Biochimica et Biophysica Acta (Netherlands)

DOI:https://doi.org/10.1016/0006-3002(62)90458-4· OSTI ID:4755140

Pande, S V; Ramaiah, A; Venkitasubramanian, T A

The effects of x radiation on the hepatic synthesis of fatty acids and cholesterol that accompany starvation were studacids and cholesterol that accompany starvation were studied. Following irradiation, 5 ml of glucose solution was given to irradiated and nonirradiated albino rats until the animals became glycosuric. lrradiated animals developed g1ycosuria 14-l8 hr after irradiation. Before being killed, the rats were injected with sodium (I-C/sup 14/ ) acetate. There was a tendency for animals force fed with glucose to incorporate (I-C/sup 14/) acetate into fatty acids and cholesterol to a greater extent than animals fed a stock diet ad libitum. lt is believed possible that decreases in the activities of the eazymes synthesizing fatty acids and cholesterol and alterations in the regulatory factors that accompany starvation are prevented as a result of irradiation. (P.C.H.)

• Research Organization: Univ. of Delhi
• NSA Number: NSA-17-005792
• OSTI ID: 4755140
• Journal Information: Biochimica et Biophysica Acta (Netherlands), Journal Name: Biochimica et Biophysica Acta (Netherlands) Vol. Vol: 65; ISSN BBACA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ALKALI METALS
ALKALINE EARTH METALS
BIOCHEMISTRY
BIOLOGY AND MEDICINE
CARBON 14
CHOLESTEROL
DIET
FATTY ACIDS
GLYCOSURIA
HALIDES
HIGH TEMPERATURE
LIVER
METABOLISM
METALS
ORGANIC ACIDS
PRODUCTION
QUANTITY RATIO
RADIATION EFFECTS
RATS
SUGARS
TRACER TECHNIQUES
URANIUM
URANIUM FLUORIDES
URINE
X RADIATION