THE GENETIC RADIOSENSITIVITY OF THE GUINEA PIG

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4754863

Plotnikova, E D; Strashenenko, S I; Shapiro, N I

Prevlous investigations of the authors (Radiobiologiya 1: 93(1961) No. 1) concerning the dependence of the frequency of dominant lethal mutations on the dose rate of the x radiation to which rabbits, rats, and mlce were exposed, was extended to include a similar study of gulnea plgs. The gonads of the male animals were locally irradlated at 300, 450, and 750 r; the animals were then mated, killing the females within the 30th and 40th day of the ensuing pregnancy. The number of corpora lutea, the place of implanta tion, and the embryos were determined and used for calculating the losses of the offspring as the result of dominant lethal mutations in the spermatozoa. Results indicated great variations in the genetic radiation sensitivity of these related animals: the frequency of the occurrence of dominant lethal mutations was considerably lower in the guinea pig than in mice, rats, or rabbits. Further studies are needed for clarifying the meaning of chromosome aberrations due to radiation. (TTT)

• Research Organization: Inst. of Biological Physics, Academy of Sciences and Academy of Medical Sciences, USSR
• NSA Number: NSA-16-032867
• OSTI ID: 4754863
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 2; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
CHROMOSOMES
EMBRYOS
GENETICS
GONADS
GUINEA PIGS
MICE
MUTATIONS
PREGNANCY
QUANTITATIVE ANALYSIS
QUANTITY RATIO
RABBITS
RADIATION DOSES
RADIATION EFFECTS
RADIOSENSITIVITY
RATS
SEX
VARIATIONS
X RADIATION