THE SUCCESSIVE CHANGES IN THE SKIN EPITHELIUM OF THE YOUNG AXOLOTL (SIREDON MEXICANUM) AFTER ROENTGEN IRRADIATION
The heads of 127 animals from one spawning were irradiated 14 days after hatching with: 9000, 6000, 3000, controls. As the amount of radiation increased, the number of days before enlarged epithelium cells were observed was decreased. For example: 21 days after irradiation with 1000 r, the cells of the epithelium were definitely enlarged, but only 17 days after irradiation 3000 r, the epithelial greatly enlarged. The threshold of sensitivity of skin epithelium is between 250 and 500 r. Giant epithelial cells were in some cases 7 to 8 times larger than the normal cells of control animals of the same age. They were 5 to 6 times larger than the other epithelial cells of the same animal in close proximity. The nuclei of the giant cells were much larger than the nuclei of normal epithelial cells. The maximal size and maximal development of the giant cell epithelium were observed after irradiation with medium doses. (P.C.H.)
- Research Organization:
- Roswell Park Memorial Inst., Buffalo
- NSA Number:
- NSA-17-014000
- OSTI ID:
- 4750010
- Journal Information:
- Am. J. Roentgenol., Radium Therapy Nucl. Med., Journal Name: Am. J. Roentgenol., Radium Therapy Nucl. Med. Vol. Vol: 89
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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