THE OCCURRENCE OF CHROMOSOMAL ABERRATIONS IN PRE-SPERMATOCYTIC CELLS OF IRRADIATED MALE MICE. Progress Report February 1, 1962-January 31, 1963
Technical Report
·
OSTI ID:4749098
An investigation was made of the nature and extent of radiation injuries to the chromosome system of prespermatocytic cells, including spermatogonia and their precursors, in male mice exposed to three dose levels of x radiation. The treated males were mated to unexposed females and offspring sired by each male throughout the remainder of his life were tested for the presence of chromosomal aberrations capable of producing semisterility. All semi-sterile lines and all sterile F/sub 1/ males were analyzed cytologically. Following irradiation of the testes an initial period of good fertility was observed for about one month, followed by a period of sterility that varied with the radiation dose, and a period of renewed fertility that continued throughout the remainder of the lifespan. Spermatogenesis ceased and spermatogonia were scarce or absent during the sterile period. (C.H.)
- Research Organization:
- Roscoe B. Jackson Memorial LAb., Bar Harbor, Me.
- NSA Number:
- NSA-17-015637
- OSTI ID:
- 4749098
- Report Number(s):
- TID-18135
- Country of Publication:
- United States
- Language:
- English
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