EFFECTS OF FEEDING A VITAMIN K-DEFICIENT RATION CONTAINING IRRADIATED BEEF TO RATS, DOGS, AND CATS
Journal Article
·
· Journal of Nutrition (U.S.)
OSTI ID:4746661
A ration containing 35% beef irradiated with 2.79 megarad fed to 12 male Sprague-Dawley rats caused the death of 9 rats because of hemorrhage. The mean reciprocal of the prothrombin time was 0.068 plus or minus 0.018 sec/sup -/. When 3 male cats and 3 male dogs were fed a ration containing irradiated bsef for 40 weeks, all gained weight and the prothrombin time of the blood remained normal. The amount of vitamin K in the ration was calculated to be 6 mu g/100 g of ration solids, which was adequate to prevent prolonged prothrombin times of the blood of cats and dogs, although it was inadequate for rats. Irradintion of beef with 2.8 megarad was previously shown to cause a 50--85% loss in vitamin K content. Rats fed a ration containing nonirradiated beef survived and there was no prolonged prothrombin time of the blood. (H.H.D.)
- Research Organization:
- Univ. of Illinois, Urbana
- NSA Number:
- NSA-17-008502
- OSTI ID:
- 4746661
- Journal Information:
- Journal of Nutrition (U.S.), Journal Name: Journal of Nutrition (U.S.) Vol. Vol: 74; ISSN JONUA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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