PARTIAL RADIODESTRUCTIONS IN THE CHICK EMBRYO OF EARLY STAGES AND LOCALIZATION OF THE DIGESTIVE RUDIMENTS

Journal Article · Wed Mar 01 04:00:00 EST 1961 · J. Embryol. Exptl. Morphol.

OSTI ID:4737222

Le Douarin, N

Portions of embryos were irradiated with a narrow x-ray beam, at stages bearing 9 to 25 somites, to study the development of certain organ rudiments. Only embryos surviving 7 days of incubation were examined. Transverse regions of the embryo localized behind a given somite (23rd, 15th, 6th, 4th, 2nd) were irradiated while the posterior region of the irradiated embryo was shielded to allow normal development of the allantois. The shielded anterior and posterior portions of the embryo always became connected by a pedicule of tissue; and sometimes a celosomic condition resulted. If the embryos were irradiated behind the 4th or 6th somite, some internal organs were often lodged in a pocket situated at the base of the neck. Destruction of the specific regions permitted localization of rudiments of different parts of the digestive tract and respiratory system. In additional experiments utilizing higher doses, irradiation of a narrow transverse zone (between the 6th and the 15th somites) produced embryos in which the part of the digestive tract corresponding to the irradiated region was present but anomalous. Also, embryos subjected to unilateral irradiation possessed a completely continuous intestine with a reduced diameter. Thus some repair of x-ray lesions is possible when the irradiated zone is limited in extent. (H.H.D.)

• Research Organization: College de France, Paris
• NSA Number: NSA-17-017849
• OSTI ID: 4737222
• Journal Information: J. Embryol. Exptl. Morphol., Journal Name: J. Embryol. Exptl. Morphol. Vol. Vol: 9
• Country of Publication: Country unknown/Code not available
• Language: French

Related Subjects

BIOLOGY AND MEDICINE
BIRDS
CHICKENS
EMBRYOS
INTESTINE
LUNGS
RADIATION INJURIES
RECOVERY
SHIELDING
STOMACH
TISSUES
X RADIATION