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PREPARATION OF TRITIATED PHENOLS. II. SYNTHESIS OF THYROID HORMONES LABELED WITH H$sup 3$ (dl-THYROXINE AND IODO-3,5,3'-dl-THYRONINE (in French)

Journal Article · · Intern. J. Appl. Radiation Isotopes
Tritium labeled /sub DL/-thyroxine and 3,5,3'-triodo-/sub DL/thyronine were synthesized using labeled hydriodic acid in a general tritiation method. Both were labeled in the alpha - BETA positions of the side chain. I/sup 131/- labeling of tritiated 3,5 diiodothyronine gave rise to double-labeled thyroxine and 3,5,3' tri-iodothyronine. The purity of the synthetic compounds was controlled, and good agreement was obtained between the experimental and the theoretical specific activities of the synthesized compounds. The position and stability of the incorporated tritium atoms were established. (P.C.H.)
Research Organization:
College de France, Paris
NSA Number:
NSA-17-018095
OSTI ID:
4736177
Journal Information:
Intern. J. Appl. Radiation Isotopes, Journal Name: Intern. J. Appl. Radiation Isotopes Vol. Vol: 13
Country of Publication:
Country unknown/Code not available
Language:
French