FURTHER STUDIES ON THE THERMALLY INDUCED AGING OF DROSOPHILA MELANOGASTER

Journal Article · Mon Oct 01 04:00:00 EDT 1962 · Journal of Gerontology (U.S.)

DOI:https://doi.org/10.1093/geronj/17.4.347· OSTI ID:4728992

Strehler, B L

It was found that exposing Drosophila to ionizing radiation actually extends life expectancy, rather than shortens it. A comparison was made of the survivorship of flies reared and housed under sterile conditions with those living in cultures containing the yeasts which normaliy accompany Drosophila and which are one of their immediate food sources. The effect of irradiation on the mortality rate, such as to produce an extension of life, was largely lost or absent when the flies were reared under absolutely aseptic conditions. It was also shown that the reguiar replenishment of the housing and food of individuaiiy housed Drosophila produces a considerable extension of the life span. Thermal shock exposures at 38.5 deg C for periods ranging from 1/2 to 3 hr (in fractionated dosages) resulted in a significant increase in the age-specific mortality rate of the flies surviving beyond 7 days after the exposure. The results suggest that denaturative processes may mimic the effects of time on the aging of Drosophila as reflected in mortality rates. (H.H.D.) time on the aging of Drosophila as reflected in mortality rates. (H.H.D.)

• Research Organization: National Heart Inst., Bethesda, Md.
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-010277
• OSTI ID: 4728992
• Journal Information: Journal of Gerontology (U.S.), Journal Name: Journal of Gerontology (U.S.) Vol. Vol: 17; ISSN JOGEA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
DROSOPHILA
DROSOPHILA MELANOGASTER
FOOD
INSECTS
LIFETIME
RADIATION EFFECTS
TEMPERATURE
YEASTS