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OPTICAL ROTATORY DISPERSION OF SOME AMINO ACIDS AND CRITERIA OF PROTEIN CONFIGURATION

Technical Report ·
OSTI ID:4727321
Rotatory dispersion of amino acids is well represented by a two-term Drude equation. The parameters of the equation are obtained by least-squares fitting with the aid of an electronic computer. using data for some 42 different wavelengths between 0.65 and 0.27 mu . Data are presented for the amino acids alanine, serine, valine, leucine, proline, aspartic acid, glutamic acid, asparagine, and lysine, in their several states of protonation and ionization. The median root mean square deviation between experimental and computed STA alpha !/sub lambda / is plus or minus 0.175 deg for the data in toto. The bearing of the data on problems of helix-random coil transition of proteins, relation of structure to optical rotation, and use of rotatory dispersion as a form of spectroscopy for attacking chemical problems was discussed. (auth)
Research Organization:
Argonne National Lab., Ill.
DOE Contract Number:
W-31109-ENG-38
NSA Number:
NSA-17-016032
OSTI ID:
4727321
Report Number(s):
TID-18142; UAC-7137
Country of Publication:
United States
Language:
English

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