IRRADIATION OF LYMPH NODES
Journal Article
·
· Clinical Science (England) Changed to Clin. Sci. Mol. Med.
OSTI ID:4724831
A method was sought for the irradiation of lymph nodes. Bi/sup 206/ attached to denatured protein and injected subcutaneously gave a high concentration of activity in draining lymph nodes and in kidney. Also, some activity remained at or near the site of injection. This offers a possible method of irradiating draining lymph nodes, either to reduce the immunological response for grafting or for radiotherapy. Factors affecting lymph node uptake are discugsed. Bi/sup 206/ protein has advantages over Au/sup 198/, since as a pure gamma emitter it would give a more uniform dose for radiotherapy of an organ with uneven uptake, and this might be particularly important if uptake is low in diseased parts of lymph nodes. For a diagnostic test it would do less damage to healthy tissue. (TCO)
- Research Organization:
- Hammersmith Hospital, London
- NSA Number:
- NSA-17-019761
- OSTI ID:
- 4724831
- Journal Information:
- Clinical Science (England) Changed to Clin. Sci. Mol. Med., Journal Name: Clinical Science (England) Changed to Clin. Sci. Mol. Med. Vol. Vol: 22; ISSN CSCIA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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