DISTRIBUTION AND KINETICS OF SODIUM (Na$sup 22$) IN MICE AND RABBITS

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Acta Isotopica

OSTI ID:4719090

Huggert, A; Odeblad, E; Soremark, R; Ullberg, S

BS>The distribution and kinetics of Na/sup 22/ in mice and rabbits were studied autoradiographically and by scintillation counting at various intervals after an intravenous injection of Na/sup 22/ in an isotonic solution. The amount of Na/sup 22/ after the steady state was reached was highest in teeth among the various organs and tissues studied and decreased in the order: teeth, cartilage, bone, urine, papillary muscle, blood vessel walls, blood, gall bladder contents, lung, kidney, amniotic fluid, heart muscle, skin, fetal brain, brain, salivary gland, intestinal contents, feces, liver, gastric mucosa, muscle, gastric contents. The kinetics of sodium in the mice and rabbits was very rapid. The steady state was reached for most of the tissues within a few minutes. The build- up of Na/sup 22/ in teeth, brain, and bones was, however, extremely prolonged. The uptake of Na/sup 22/ in the fetal brain and spinal cord was significantly higher than that in the maternal brain and spinal cord. (P.C.H.)

• Research Organization: Medical School, Omea, Sweden; Sabbatsberg Hospital, Stockholm; Royal School of Dentistry, Stockholm; and Veterinary School, Stockholm
• NSA Number: NSA-17-021429
• OSTI ID: 4719090
• Journal Information: Acta Isotopica, Journal Name: Acta Isotopica Vol. Vol: 1
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BILE
BIOLOGY AND MEDICINE
BLOOD
BLOOD VESSELS
BONES
BRAIN
CARTILAGE
DISTRIBUTION
FECES
FETUSES
GLANDS
HEART
INTESTINE
KIDNEYS
LIVER
LUNGS
METABOLISM
MICE
MUSCLES
NERVOUS SYSTEM
QUANTITY RATIO
RABBITS
RADIOAUTOGRAPHY
SALIVARY GLANDS
SCINTILLATION COUNTERS
SKIN
SODIUM 22
SPINAL CORD
STOMACH
TEETH
TISSUES
URINE