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EFFECT OF NATURAL AND PURIFIED DIETS ON SURVIVAL OF X-IRRADIATED MICE

Journal Article · · Radiation Res.
DOI:https://doi.org/10.2307/3571390· OSTI ID:4717050

After a 7-day feeding of either natural or purified types of diet, the effects of a high-level (LD/sub 90/) dose of 750 r of whole-body x irradiation given at a dose rate of 45 r/min were determined by 30-day survival of mice. Dietary variables in the five natural diets included simple and complex formulation and vitamin and mineral supplementation. The five purified diets contained different moisture and lipid levels. One diet was supplemented with yeast, a natural product. Average 30- day per cent survival of x irradiated mice fed the purifled diets was signiflcantly greater (34%) than that of similarly irradiated mice fed the natural diets (16%). However, when the purified diets were made up in a 52% moisture agar gel form, average survival was reduced to 10%. The reasons for the survival differences are unknown. Nevertheless, the data add further support to the contention that the diet can be an important factor in the response of organisms to ionizing radiation exposure. (auth)

Research Organization:
Massachusetts Inst. of Tech., Cambridge
Sponsoring Organization:
USDOE
NSA Number:
NSA-17-023181
OSTI ID:
4717050
Journal Information:
Radiation Res., Journal Name: Radiation Res. Vol. Vol: 18
Country of Publication:
Country unknown/Code not available
Language:
English

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