Diffusely discordant In-111 WBC/Tc-99m SC bone marrow uptake: A possible chemotherapeutic effect
Journal Article
·
· Clinical Nuclear Medicine
- New England Medical Center and Tufts Univ. School of Medicine, Boston, MA (United States)
In-111 WBC scintigraphy in a women with relapsed acute lymphoid leukemia demonstrated normal uptake of white blood cells by the liver and spleen, but virtually absent bone marrow activity. Tc-99m Sc imaging confirmed normal marrow function and distribution. A bone marrow biopsy revealed mildly hypocellular, regenerating marrow without leukemic infiltration. The effects of systemic cytotoxic chemotherapy on marrow reticuloendothelial function may have been responsible for this discordant uptake. 5 refs., 2 figs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 471565
- Journal Information:
- Clinical Nuclear Medicine, Journal Name: Clinical Nuclear Medicine Journal Issue: 7 Vol. 20; ISSN 0363-9762; ISSN CNMEDK
- Country of Publication:
- United States
- Language:
- English
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