INHIBITORY EFFECT OF PREIRRADIATION SACCHARIN HABITUATION ON CONDITIONED AVOIDANCE BEHAVIOR

Journal Article · Mon Apr 01 04:00:00 EST 1963 · Radiation Res.

DOI:https://doi.org/10.2307/3571391· OSTI ID:4712548

McLaurin, W A; Farley, J A; Scarborough, B B

A total of 40 male and female albino rats were assigned to four treatment groups with 10 subjects in each group. Three groups were given a 6-day period of habituation to a 0.1% saccharin solution with an interpolated interval of 0, 3, or 6 days on tap water between the end of the 6-day habituation period and the irradiation exposure. The control group had no preirradiation habituation to the saccharin solution. All groups were permitted to drink the 0.1% saccharin solution for 30 minutes and then were exposed to whole-body irradiation for 15 minutes, which resulted in a summated exposure dose of 102 r in air. Preirradiation habituation to saccharin solution was found to have a signiflcant inhibitory effect on conditioned avoidance behavior. Intervals of 3 and 6 days on tap water between the end of the habituation period and radiation exposure showed mixed effects over days, but all habituated groups were significantiy different from the nonhabituated group except the 6-day interval group on the first postirradiation day. (auth)

• Research Organization: Florida State Univ., Tallahassee
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-023182
• OSTI ID: 4712548
• Journal Information: Radiation Res., Journal Name: Radiation Res. Vol. Vol: 18
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AIR
BEHAVIOR
BIOLOGY AND MEDICINE
BODY
DRUGS
GENETICS
QUANTITY RATIO
RADIATION DOSES
RATS
SEX
SOLUTIONS
VARIATIONS
WATER