THE EFFECT OF RADIATION ON THE LIPO-PROTEIN CONTENT OF THE LIVER MITOCHONDRIA AND THE PHOSPHATIDES IN THE RABBIT SERA AND THE PROTECTIVE INFLUENCE OF VITAMIN B$sub 6$ ON THIS PROCESS

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4705838

Mosin, A F

The effect of vitamin B/sub 6/ on the lipoprotein content in the various cell components was investigated, comparing the results with the phosphatide content in the blood sera of the irradiated animals. The tests were carried out on the liver mitochondria and blood sera of rabbits. Vitannin B/sub 6/ was administered at the rate of 3 mg pyridoxine base per kg weight for eight days once daily to test animals that were subsequently exposed to 1000 r of x radiation at a rate of 18 r/min, killing the animals 12 hours after the irradiation. It was found that after irradiation alone the amount of lipoproteins in the liver mitochondria was lowered to 26% while the lipid phosphorous content of the serum was increased. Administration of vitamin B/sub 6/ in most cases prevented completely or reduced the subsequent changes in both the lipoprotein content of the liver mitochondria and the lipid P of the blood serum. The amount of lipid P in the liver mitochondria of the irradiated and unirradated rabbits was identical. (TTT)

• Research Organization: Inst. of Experimental Medicine, Leningrad
• NSA Number: NSA-17-030350
• OSTI ID: 4705838
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 3; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE
BLOOD SERUM
CYTOLOGY
LIPIDS
LIVER
MITOCHONDRIA
PHOSPHORUS COMPOUNDS
PROTEINS
QUANTITY RATIO
RABBITS
RADIATION DOSES
RADIATION EFFECTS
SURVIVAL TIME
TESTING
VARIATIONS
VITAMIN B-6
VITAMINS
WEIGHT
X RADIATION