ROLE OF THE MIDBRAIN COVERING AND SUBTHALAMUS IN THE EARLY BIOELECTRIC REACTION OF THE RABBIT BRAIN CORTEX TO WHOLE-BODY IONIZING IRRADIATION

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4694548

Lebedev, A N

With the objective of clarifying the manner in which the midbrain covering effects the reaction of the cortex as a result of irradiation, the reticular formation was destroyed in 5 rats and the subthalarnus in 7. There were six unoperated controls. A definite similarity was observed in the radiation reaction of the cortex of the two operated groups, the development of an early bioelectric reaction in the cortex following 1000 r irradiation being similar. The general conditions of the animals changed greatly: breathing became infrequent, pulses became faster, motor activity decreased progressively, fur fell out, appetite disappeared, stools became liquid with blood, and weight declined. All animals died the first day after irradiation. Anatomically it has been shown that the path from the covering of the midbrain to the cortex is through the subthalamus. Therefore the path is most probably the same in the irradiated animal. Charts are given which show the electroencephalograms before and after irradiation, with electrocardiograms, light stimulation response, and breathing of animals of the two operated groups. (TTT)

• Research Organization: Inst. of Higher Nerve Action and Neurophysiology, Moscow
• NSA Number: NSA-17-031934
• OSTI ID: 4694548
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 3; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

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BIOLOGY AND MEDICINE