THE DIAGNOSIS OF FEMALE GENITAL TUMORS WITH RADIOISOTOPES (in Italian)
Journal Article
·
· Minerva Nucleare (Italy) Ceased publication with Vol. 9, no. 6, 1965 Divided into G. Fis. Sanit. Prot. Radiaz. and J. Nucl. Biol. Med.
OSTI ID:4690806
The use of radioactive tracer substances for demonstrating the early stages of tumors of the genital organs is considered. As regards the external genital organs, patients with acute or chronic vulvitis, kraurosis vulvar with or without leukoplakia, and cancer were examined by measuring the radioactivity with a Geiger-Muller counter 6, 24, and 48 hr after the injection of 3 C of P/sup 32/ per kg of body weight. The results indicate that investigation of the uptake of radiophorphorus in the vulva can yield valuable information as to the nature of the various conditions considered. Measurements were made with a Geiger-Muller probe counter over the portio in normal cases and in patients with different types of disease (erosions, polyps, cancer) at various intervals after the injection of the same dose of P/sup 32/ intravenously. It was shown that a high uptake can be demonstrated in vivo in the neoplastic tissues as compared with the normal tissues. The difference is most significant between the 48th and 72nd hr, when the values measured over erosions and polyps remain within the range of normal. The method therefore makes it possible to identify areas of neoplastic tissue in the portio and to establish their boundaries faily well. The uptake of P/sup 32/ was investigated in cases of cancer of the neck of the uterus before and after radium therapy. It was found that the method is valuable in establishing the prognosis and as a method for controlling the effects of irradiation. Finally, the results obtained in the field of the diagnosis of ovarian tumors with the use of gamma-emitting tracer substances (radioiodinated human serum albumin and I/sup 131/-labeled diiodofluorescein) and those of intra- operative investigation of lymph nodes containing metastases in cases of cancer of the cervix after the administration of P/sup 32/ are presented. The importance of the method, especially as regards the possibilities of completely removing all lymph nodes involved by the tumor, is discussed. (auth)
- Research Organization:
- Universita, Pisa, Italy
- NSA Number:
- NSA-17-026995
- OSTI ID:
- 4690806
- Journal Information:
- Minerva Nucleare (Italy) Ceased publication with Vol. 9, no. 6, 1965 Divided into G. Fis. Sanit. Prot. Radiaz. and J. Nucl. Biol. Med., Journal Name: Minerva Nucleare (Italy) Ceased publication with Vol. 9, no. 6, 1965 Divided into G. Fis. Sanit. Prot. Radiaz. and J. Nucl. Biol. Med. Vol. Vol: 7; ISSN MINUA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Italian
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