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In Vivo Counting Sr-85 in Studies of Calcium Metabolism and Bone Lesion (in Japanese)

Journal Article · · Proc. Japan Conf. Radioisotopes
Clinical diagnostic applications of an area scanner, linear scanner, and whole-body counter for radioisotope studies of Ca metabolism and bone lesions are described. Tracer doses (1 mu C/kg body weight for scanning, 0.1 mu C/kg body weight for whole-body counting) of Sr/sup 85/ were injected intravenously to 20 selected subjects (5 normal, 2 with tetanus, 1 with Albright's syndrome, 1 with chondrodystrophia, 5 metastatic bone tumor, and 6 primary bone tumor). The whole- body retention of Sr/sup 85/ was measured with a wholebody counter equipped with two large (25- x 20- x 10-cm) plastic scintillators for a period of about 10 days. The results obtained from area and linear scans showed that significant localization of Sr/sup 85/ occurred in the knee and heel joints of subjects under 20 years of age, and in particular, in cases where the lesions were progressing. Six subjects were studied for Sr/sup 85/ whole-body retention. Significant differences in the retention were found in patients with chondrosarcoma and Albright's syndrome. It was concluded that Sr/sup 85/ studies may give important information on the dynamic state of Ca metabolism bone lesions even before visualization on radiographs. (P.C.H.)
Research Organization:
National Inst. of Radiological Sciences, Chiba
Sponsoring Organization:
USDOE
NSA Number:
NSA-17-030211
OSTI ID:
4688940
Journal Information:
Proc. Japan Conf. Radioisotopes, Journal Name: Proc. Japan Conf. Radioisotopes Vol. Vol: 5th, No. 4
Country of Publication:
Country unknown/Code not available
Language:
Japanese

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Related Subjects

AGE
BODY
BONES
CALCIUM
DETECTION
DIAGNOSIS
DISEASES
GENERAL AND MISCELLANEOUS
MEASURED VALUES
METABOLISM
OSTEOPOROSIS
POLYMERS
RADIATION DETECTORS
RADIOGRAPHY
RADIOISOTOPES
SCINTILLATION COUNTERS
STRONTIUM 85
TRACER TECHNIQUES
TUMORS
USES
WEIGHT