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Dissociation of Homograft Response to Allogeneic versus Xenogeneic Skin Grafts in Irradiated Mice

Journal Article · · Science
Lethally x-irradiated (C3H x DBA/2)F1 mice were protected with syngeneic (isogenic) bone marrow and/or prior treatment with urethan and skin grafted at various times after irradiation. The ability to reject a first-set xenogeneic (heterologous) skin graft with normal vigor returned within 92 days; the first-set response to allogeneic (homologous) grafts was still impaired 350 days after irradiation.
Research Organization:
Naval Radiological Defense Lab., San Francisco
Sponsoring Organization:
USDOE
NSA Number:
NSA-17-033749
OSTI ID:
4683489
Journal Information:
Science, Journal Name: Science Journal Issue: 3583 Vol. 141; ISSN 0036-8075
Publisher:
AAAS
Country of Publication:
Country unknown/Code not available
Language:
English