The Behavior of Strontium-85 in a Normal Man Following a Single Ingestion—Absorption and Excretion

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Health Physics

DOI:https://doi.org/10.1097/00004032-196304000-00004· OSTI ID:4680619

Fujita, M.; Yabe, A.; Ueno, K.; Oshino, M.; Okuyama, N.

The rate of fecal and urinary excretion of strontium-85 following a single ingestion, in a normal adult, was measured up to 162 days. Large amounts of unabsorbed strontium were found in the feces during the first 3 days, and only 13.6 per cent of the dose was absorbed. The absorbed portion of the radioactivity showed the turnover of a threestage process, (1) rapid excretion, (2) an intermediate-rate process, and (3) a chronic retention stage, in accordance with the dose injected intravenously. The urinary-total excretion ratio was 2/3 except for the first 3 days. The variation of plasma concentration of strontium-85 was measured over the first 44 hr after ingestion, and calcium intake and excretion were also measured. It is shown that the urinary excretion of strontium-85 is closely linked with that of calcium and the plasma concentration of strontium-85.

• Research Organization: Japan Atomic Energy Research Inst., Tokyo
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-024855
• OSTI ID: 4680619
• Journal Information: Health Physics, Journal Name: Health Physics Journal Issue: 4 Vol. 9; ISSN 0017-9078
• Publisher: Health Physics Society
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AGE
BLOOD PLASMA
CALCIUM
FECES
MAN
METABOLISM
QUANTITY RATIO
STRONTIUM 85
URINE