Bone Marrow Lipids in Rats Exposed to Total-Body Irradiation
ABS>Thin-layer chromatography was used to demonstrate that bone marrow lipids of rats were primarily triglycerides; gas-liquid chromatography of the fraction revealed that palmitic and oleic acids account for more than 80% of the fatty acids. Minor lipid components present in the control and irradiated marrow are glyceryl ethers, cholesterol, fatty acids, and phospholipids. Cholesterol esters were not found. Total-body irradiation (800 r) increases the femur marrow triglyceride fraction approximately six times by 1 week after irradiation, and it remains elevated for many weeks. The relationship between dose and increase in marrow triglycerides appears to fit the equation y = bxa. The water and lipid content of bone marrow bear a reciprocal relation to each other, while both water and residue are significantly reduced in the irradiated femur marrow.
- Research Organization:
- Oak Ridge Inst. of Nuclear Studies, Tenn.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-17-024970
- OSTI ID:
- 4679560
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 1 Vol. 19; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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