Sequence analysis of the cDNA for the human casein kinase I {delta} (CSNK1D) gene and its chromosomal localization
- Univ. of Tokyo (Japan)
This article reports on the genetic mapping of a cDNA clone encoding human casein kinase I (CK1) using fluorescence in situ hybridization and polymerase chain reaction analysis of human-rodent hybrid cell panels. When compared to the amino acid sequence in the kinase domain of the rat, this cDNA seems to be a human homologue of the CK1 {delta} isoform. Sequence similarity to the kinase domains and function in DNA repair in Saccharomyces cerevisiae and Saccharomyces pombe are discussed. 14 refs., 2 figs.
- OSTI ID:
- 466410
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 1 Vol. 32; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
55 BIOLOGY AND MEDICINE
BASIC STUDIES
AMINO ACID SEQUENCE
CASEIN
DNA
DNA HYBRIDIZATION
DNA REPAIR
DNA SEQUENCING
DNA-CLONING
FLUORESCENCE
GENE MUTATIONS
GENE RECOMBINATION
GENETIC MAPPING
HUMAN CHROMOSOME 17
METABOLISM
NUCLEOTIDES
PHOSPHOTRANSFERASES
POLYMERASE CHAIN REACTION
RATS
SACCHAROMYCES CEREVISIAE
SERINE
SOMATIC CELLS
STRAND BREAKS
THREONINE
BASIC STUDIES
AMINO ACID SEQUENCE
CASEIN
DNA
DNA HYBRIDIZATION
DNA REPAIR
DNA SEQUENCING
DNA-CLONING
FLUORESCENCE
GENE MUTATIONS
GENE RECOMBINATION
GENETIC MAPPING
HUMAN CHROMOSOME 17
METABOLISM
NUCLEOTIDES
PHOSPHOTRANSFERASES
POLYMERASE CHAIN REACTION
RATS
SACCHAROMYCES CEREVISIAE
SERINE
SOMATIC CELLS
STRAND BREAKS
THREONINE