RADIATION REACTIONS AND RADIATION LESIONS IN THE EYE

Journal Article · Fri Dec 01 04:00:00 EST 1961 · Wien. Klin. Wochschr.

OSTI ID:4661231

Wachtler, F

Radiation injury to the eye is discussed in terms of the induction of radiation cataract and retinopathy, and the early changes in the cornea and connective tissue of the eye. Evaluation of 100 reported cases shows that the minimum dose of x and gamma rays required to cause cataract is approximates 200 r in a single exposure. With repeated doses spaced over 3 weeks to 3 months the minimum total cataractogenic dose appears to be approximates 400 r. Lower doses of neutrons can cause cataract, while up to 8000-r doses from Sr/sup 90/ may be tolerated. The lens appears to be 2 to 3 times more sensitive in young than in adult animals, and radiotherapy for eye tumors in children is more likely to induce cataract than similar treatment of adults. The retina is relatively less sensitive and a pathologic electroretinogram is obtained only at doses above 2000 r. After 10,000 r functional disturbances are more evident, and after 30000 r severe injury to the ganglion cells can be seen. Early changes in the cornea and ocular connective tissue are evident only after high doses; keratitis and conjunctivitis may follow 5000 r, and corneal ulceration after 10,000 r. Some clinical findings in patients given radiotherapy for various types of eye tumors are described. (TCO)

• Research Organization: Universitat, Vienna
• NSA Number: NSA-17-027186
• OSTI ID: 4661231
• Journal Information: Wien. Klin. Wochschr., Journal Name: Wien. Klin. Wochschr. Vol. Vol: 73
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
ANIMALS
BIOLOGY AND MEDICINE
CATARACTS
CONJUNCTIVITIS
DOSE FRACTIONATION
EYES
GAMMA RADIATION
KERATITIS
MAN
MEDICINE
NERVOUS SYSTEM
NEUTRONS
RADIATION DOSES
RADIATION INJURIES
RADIOTHERAPY
STATISTICS
STRONTIUM 90
TISSUES
TUMORS
X RADIATION