Molecular cloning and characterization of the mouse CGT gene encoding UDP-galactose ceramide-galactosyltransferase (cerebroside synthetase)

Journal Article · Mon Jul 01 00:00:00 EDT 1996 · Genomics

DOI:https://doi.org/10.1006/geno.1996.0342· OSTI ID:466038

Bosio, A; Binczek, E; Stoffel, W ^[1]

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1. Universitaet Koeln, Cologne (Germany)

UDP-galactose ceramide galactosyltransferase, CGT, EC 2.4.1.45, is the key enzyme in the biosynthesis of cerebrosides and sulfatides, which are the most abundant glycosphingolipids in the myelin of the central nervous system and the peripheral nervous system.

• OSTI ID: 466038
• Journal Information: Genomics, Vol. 35, Issue 1; Other Information: PBD: 1 Jul 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
HUMAN CHROMOSOMES
GENETIC MAPPING
ANIMAL CELLS
CELL DIFFERENTIATION
HEXOSYL TRANSFERASES
DNA-CLONING
GENE REGULATION
BIOLOGICAL EVOLUTION
STRUCTURE-ACTIVITY RELATIONSHIPS
TRANSCRIPTION
SPLICING
CEREBROSIDES
BIOSYNTHESIS
NUCLEOTIDES
MICE
AMINO ACID SEQUENCE
DNA SEQUENCING
DNA HYBRIDIZATION
MYELIN