A comparison of numerical simulations and laboratory studies of laser thrombolysis
Conference
·
OSTI ID:461423
- Los Alamos National Lab., NM (United States)
- Oregon Graduate Inst. and Oregon Medical Laser Center, Portland, OR (United States)
We compare Los Alamos numerical simulations with Oregon Medical Laser Center laser deposition experiments conducted with gelatin thrombus surrogates specifically chosen for relevance to clinical laser thrombolysis. Initial idealized calculations suggest that a surprisingly large fraction of the absorbed laser energy is dissipated as acoustic radiation. We build on these results here by investigating geometrical effects, material property variations, and sources of dissipation including viscosity and plastic flow, as well as acoustic radiation in an effort to explain flow effects observed in the experiments. In particular, strong jetting is observed in the simulations when the gelatin is given a kinematic viscosity in excess of {approx} 1.0 cm{sup 2}/s. Jetting is clearly evident in the experiments.
- Research Organization:
- Los Alamos National Lab., NM (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 461423
- Report Number(s):
- LA-UR--97-377; CONF-970231--23; ON: DE97004766
- Country of Publication:
- United States
- Language:
- English
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