Influence of caffeine on repair processes after uv irradiation

Journal Article · Mon Jan 01 04:00:00 EST 1973 · Stud. Biophys., v. 36-37, pp. 259-262

OSTI ID:4437697

Soska, J; Necasova, J

From international conference on the bases of the biological effects of ultraviolet radiation; Brno, Czechoslovakia (2 Oct Glucose starvation prior to uv irradiation of lactobacillus acidophilus results in a shoulder on the dose- survival curve, but, in contrast to amino acld prestarvation, this shoulder is not prevented by simultaneous thymidine starvation. Caffeine treatment after uv irradiation also causes a shoulder and increases survival. The hypothesis is put forward that the excision system of lactobacillus contributes to the cell death after irradiation and that the inhibition of excision by caffeine allows other repair systems to operate. The shoulder is then the result of a nonexcision repair system. (auth)

• Research Organization: Inst. of Biophysics, Brno
• NSA Number: NSA-29-000572
• OSTI ID: 4437697
• Journal Information: Stud. Biophys., v. 36-37, pp. 259-262, Journal Name: Stud. Biophys., v. 36-37, pp. 259-262; ISSN STBIB
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*AMINO ACIDS-- RADIOSENSITIVITY EFFECTS
*CAFFEINE-- RADIOSENSITIVITY EFFECTS
*GLUCOSE-- RADIOSENSITIVITY EFFECTS
*LACTOBACILLUS-- BIOLOGICAL RADIATION EFFECTS
*THYMIDINE-- RADIOSENSITIVITY EFFECTS
BIOLOGICAL REPAIR
CELL KILLING
N48310* --Life Sciences--Radiation Effects on Microorganisms- -Basic Studies
PHOTON BEAMS
RADIATION DOSES
RESPONSE MODIFYING FACTORS
SURVIVAL CURVES
ULTRAVIOLET RADIATION