Production of carrier-free H$sup 11$CN for medical use and radiopharmaceutical syntheses. IX
Journal Article
·
· J. Nucl. Med., v. 14, no. 11, pp. 864-866
OSTI ID:4424751
A system for the routine production of carrier-free, high-activity H/sup 11/CN in an on-line process in the effluent stream from a cyclotron gas target is described. The method is highly reproducible and trouble free, and the yields from a given target and synthesis system are entirely predictable. The material is available in the gas phase or in basic solution within 10 to 12 min after the end of the irradiation. With a current of 30 mu A of focused 25-MeV protons impinging on the target, 2 Ci of carrier-free H/sup 11/CN are produced with the present system in a 45-min irradiation. The material has been used in the preparation of carrier-free /sup 11/C-dopamine and /sup 11/C-nonrepinephrine for animal studies, and some investigation has been made of its possible use for blood labeling. (auth)
- Research Organization:
- Brookhaven National Lab., Upton, NY
- NSA Number:
- NSA-29-000217
- OSTI ID:
- 4424751
- Journal Information:
- J. Nucl. Med., v. 14, no. 11, pp. 864-866, Journal Name: J. Nucl. Med., v. 14, no. 11, pp. 864-866; ISSN JNMEA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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