Acute mortality and changes in body-weight of mice after partial-body irradiation with x rays and fast neutrons

Journal Article · Sat Sep 01 04:00:00 EDT 1973 · Int. J. Radiat. Biol., v. 24, no. 3, pp. 275-283

DOI:https://doi.org/10.1080/09553007314551111· OSTI ID:4421305

Matsuzawa, H; Kawashima, K; Inada, T; Hiraoka, T; Shiragai, A; Sato, F; Tsuchihashi, S

Acute mortality and changes in body =weight were studied in CRF/sub 1/ female mice after trunk irradiation with 200-kV x rays and fast neutrons produced by the Be(d,n) reaction with 2.8-MeV deuterons. For the neutron beam, including its inherent gamma contamination, LD/sub 50/ values of 412 rads and 527 rads and RBE values of 3.1 and 2.7 were obtained for 30-day mortality and 5 day mortality, respectively. For changes in body-weight of surviving mice, a single minimum was found after trunk irradiation with x rays as well as neutrons. The minimum weight, the time at which this occurred, and the time of recovery to the initial weight level were correlated with dosage. (auth)

• Research Organization: National Inst. of Radiological Sciences, Chiba, Japan
• NSA Number: NSA-29-002934
• OSTI ID: 4421305
• Journal Information: Int. J. Radiat. Biol., v. 24, no. 3, pp. 275-283, Journal Name: Int. J. Radiat. Biol., v. 24, no. 3, pp. 275-283; ISSN IJRBA
• Country of Publication: United Kingdom
• Language: English

Related Subjects

*FAST NEUTRONS-- RBE
*MICE-- BIOLOGICAL RADIATION EFFECTS
BODY
COMPARATIVE EVALUATIONS
DOSE-RESPONSE RELATIONSHIPS
KEV RANGE 100-1000
LETHAL RADIATION DOSE
MORTALITY
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
NEUTRON BEAMS
PARTIAL BODY IRRADIATION
PHOTON BEAMS
RESPONSE MODIFYING FACTORS
TIME DEPENDENCE
WEIGHT
X RADIATION