The Mouse Thyroid and Radioactive Iodine (I¹³¹) 1. General Morphology of Thyroid Gland

Technical Report · Thu Mar 01 00:00:00 EST 1951

DOI:https://doi.org/10.2172/4411868· OSTI ID:4411868

Rugh, Roberts ^[1]

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1. Columbia Univ., New York, NY (United States)

This is the first of a series of papers which will deal extensively with the effect of radioactive iodine (I¹³¹) on the mouse, both the adult female and its suckling young. Since the thyroid gland is known to have a strong avidity for iodine, this gland will be the center of interest throughout the series although a total of 11 tissues and the residual carcass will also be analyzed. The study includes the excretion rate; the tissue distribution; and the histopathology of both the thyroid and the pituitary glands in both the mother aid her suckling young, at various intervals after the mothers are given single injections of varying doses of carrier-free Na I¹³¹.

• Research Organization: Columbia Univ., New York, NY (United States)
• Sponsoring Organization: US Atomic Energy Commission (AEC)
• DOE Contract Number: AT-30-1-GEN-70
• OSTI ID: 4411868
• Report Number(s): NYO--1544
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE
BIOLOGY AND MEDICINE
DISTRIBUTION
IODINE 131
LABELLED COMPOUNDS
METABOLISM
MICE
RADIATION EFFECTS
RADIOAUTOGRAPHY
SODIUM IODIDES
THYROID
TOXICITY