Effect of rec mutations on the ultraviolet protecting and mutation- enhancing properties of the plasmid R-Utrecht in Salmonella typhimurium

Journal Article · Sat Sep 01 00:00:00 EDT 1973 · Mutat. Res., v. 19, no. 3, pp. 357-359

DOI:https://doi.org/10.1016/0027-5107(73)90237-6· OSTI ID:4407765

MacPhee, D G

Derivatives of strains of S. typhimurium with and without H-Utrecht were tested for their ability to yield uv-induced back mutations of the amber mutation. Results showed that R-Utrecht significantly enhanced the uv mutability of one strain, but cells of another strain were stable to the mutagenic effects of uv whether or not R-Utrecht is present. It was concluded that because the R-Utrecht factor does not restore uv resistance or uv mutability to the recA-type mutants, it seems unlikely that the effects of the R factor on the uv response of wild- type cells could be due to a plasmid gene whose product is functionally equivalent to that of the chromosomal recA. (HLW)

• Research Organization: La Trobe Univ., Bundoora, Australia
• Sponsoring Organization: USDOE
• NSA Number: NSA-29-002848
• OSTI ID: 4407765
• Journal Information: Mutat. Res., v. 19, no. 3, pp. 357-359, Journal Name: Mutat. Res., v. 19, no. 3, pp. 357-359; ISSN MUREA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*GENES-- RADIOSENSITIVITY EFFECTS
*MUTATIONS-- RADIOINDUCTION
*SALMONELLA TYPHIMURIUM-- MUTATIONS
GENETIC RADIATION EFFECTS
MUTANTS
N48310* --Life Sciences--Radiation Effects on Microorganisms- -Basic Studies
PHOTON BEAMS
RESPONSE MODIFYING FACTORS
ULTRAVIOLET RADIATION