Atropine-caused central nervous system interference with radiation-induced learned and unlearned behaviors

Journal Article · Wed Oct 31 23:00:00 EST 1973 · Int. J. Radiat. Biol., v. 24, no. 5, pp. 463-468

DOI:https://doi.org/10.1080/09553007314551341· OSTI ID:4392095

Gould, M N; Yatvin, M B

The inhibition by atropine of radiation-induced conditioned saccharine aversion (RCSA) and unconditioned bizarre eating in the rat was investigated. Atropine sulphate interfered with the two behavioral responses, but atropine methylnitrate did not. This supports the conclusion that the central nervous system is the site of atropine interference. Funthermore, RCSA was inhibited when atropine sulphate was given either before or after irradiation and conditioning, indicating that the presence of the drug during the acquisition of RCSA was not necessary for this behavioral blockage. (auth)

• Research Organization: Univ. of Wisconsin, Madison
• NSA Number: NSA-29-010458
• OSTI ID: 4392095
• Journal Information: Int. J. Radiat. Biol., v. 24, no. 5, pp. 463-468, Journal Name: Int. J. Radiat. Biol., v. 24, no. 5, pp. 463-468; ISSN IJRBA
• Country of Publication: United Kingdom
• Language: English

Related Subjects

*ATROPINE-- RADIOSENSITIVITY EFFECTS
*RATS-- BEHAVIOR
BIOLOGICAL RADIATION EFFECTS
CENTRAL NERVOUS SYSTEM
DIET
LEARNING
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
RESPONSE MODIFYING FACTORS
SACCHARIN
TIME DEPENDENCE