Biological indicators and the effectiveness of sterilization procedures

Conference · Mon Jan 01 04:00:00 EST 1973

OSTI ID:4389661

Macek, T J; Phillips, G B ^[1]

---

1. ed.

From International symposium on industrial sterilization; Amsterdam, Netherlands (Sep 1972). See CONF-7209100-. A discussion is presented of the measurement of death and survival of microorganisms following sterilization treatments with steam, dry heat. and gases such as ethylene oxide, propylene oxide, and formaldehyde. Direct and indirect effects of ionizing radiation on microorganisms are discussed. The relationship of the medium, temperature, concentration of solutes, pH, and gases of the environment to the indirect action of radiation is discussed. The dose of radiation required to sterilize medical devices, drugs, and biomedical products is considered. Bacteria used as biological indicators include bacillus subtilis, B. pumilus, and Micrococcus radiodurans. (HLW)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-29-005303
• OSTI ID: 4389661
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

*MEDICAL SUPPLIES-- RADIOSTERILIZATION
*MICROORGANISMS-- STERILIZATION
BACTERIA
BIOLOGICAL RADIATION EFFECTS
CULTURE MEDIA
DRUGS
GASES
IONIZING RADIATIONS
N48310* --Life Sciences--Radiation Effects on Microorganisms- -Basic Studies
PH VALUE
RADIATION DOSES
RADIOSTERILIZATION
SURVIVAL TIME
TEMPERATURE DEPENDENCE MEDICAL SUPPLIES