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Effect of whole-body irradiation with x rays on the formation of immunity in tetanus toxoid-immunized mice. Part 2. Secondary immunity to tetanus toxin (in Polish)

Journal Article · · Med. Dosw. Mikrobiol., v. 24, pp. 247-253
OSTI ID:4389478

White mice were twofold immunized with various doses of adsorbed tetanus toxoid and irradiated with a dose of 500 R at various time intervals before and after the second immunization. The secondary response of the animals was more resistant to irradiation than the primary one. It was found, however, that antibody synthesis was disturbed in mice irradiated 1 to 2 hrs prior to the second immunization. The detrimental effect of irradiation was found to depend to a high extent on antigen dose used for the first, and not the second, immunization. (auth)

Research Organization:
Panstwowy Zaklad Higieny, Warsaw
NSA Number:
NSA-29-005335
OSTI ID:
4389478
Journal Information:
Med. Dosw. Mikrobiol., v. 24, pp. 247-253, Journal Name: Med. Dosw. Mikrobiol., v. 24, pp. 247-253; ISSN MDMIA
Country of Publication:
Country unknown/Code not available
Language:
Polish

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