Influence of genotype and neonatal irradiation upon open-field locomotion and elimination in mice

Journal Article · Fri Jun 01 04:00:00 EDT 1973 · J. Comp. Physiol. Psychol., v. 83, no. 3, pp. 458-464

DOI:https://doi.org/10.1037/h0034659· OSTI ID:4389237

Nash, D J

A diallel genetic analysis was used in a study of postnatal behavior of mice that were exposed to neonatal irradiation. Five levels of exposure were used: 0, 50, 100, 200, or 300 roentgens. Locomotion and elimination in the open field were tested at 49 days of age. Decreases in body weight and locomotion were observed. Heterosis was evident in locomotion and elimination, hybrids being more active (18%) and eliminating more (39%) than inbreds. Other genetic influences on behavior were noted in the significant differences among inbreds, in general, combining ability and maternal effects. Results demonstrate that the genetic mechanisms underlying control of locomotion and elimination in the open field are complex and that specific interactions may exist among the sexes and genotypes in nonirradiated, as well as irradiated, animals. (auth)

• Research Organization: Colorado State Univ., Fort Collins
• Sponsoring Organization: USDOE
• NSA Number: NSA-29-005352
• OSTI ID: 4389237
• Journal Information: J. Comp. Physiol. Psychol., v. 83, no. 3, pp. 458-464, Journal Name: J. Comp. Physiol. Psychol., v. 83, no. 3, pp. 458-464; ISSN JCPPA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGICAL RADIATION EFFECTS
GENOTYPE
IRRADIATION
N48520* --Life Sciences--Radiation Effects on Animals-- Vertebrates
PHOTON BEAMS
RESPONSE MODIFYING FACTORS
X RADIATION