Sensitivity of the mouse oocytes to the induction of translocations by ionizing radiations
Female mice from the C57Bl strain received 0, 50, or 200 R doses of whole-body x irradiation and were mated to control males from the same strain. Using an air-drying technique, the testes of the F/sub 1/ males were analyzed for the presence of chromosome rearrangements, but no translocation configurations were observed in the dividing spermatocytes of the 100 control males and of the 185 F/sub 1/ sons from irradiated females. Since meiotic preparations made one day after exposure of the females to x irradiation showed the presence of chromosome rearrangements in some first meiotic metaphases, it could be inferred that the absence of translocated offspring after maternal x ray exposure probably resulted from germinal selection. (auth)
- Research Organization:
- Nuclear Energy Study Center, Mol, Belg.
- NSA Number:
- NSA-29-008040
- OSTI ID:
- 4367476
- Journal Information:
- Can. J. Genet. Cytol., v. 15, no. 2, pp. 363-366, Other Information: Orig. Receipt Date: 30-JUN-74; Bib. Info. Source: CAN (Atomic Energy Commission Limited)
- Country of Publication:
- Canada
- Language:
- English
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Related Subjects
*CHROMOSOMAL ABERRATIONS- RADIOINDUCTION
*MICE- GENETIC RADIATION EFFECTS
*MUTATIONS- RADIOINDUCTION
*OOCYTES- CHROMOSOMAL ABERRATIONS
ANIMAL CELLS
BIOLOGICAL RADIATION EFFECTS
CROSSING-OVER
DOSE-RESPONSE RELATIONSHIPS
FEMALES
IRRADIATION
MALES
MEIOSIS
PROGENY
SPERMATOZOA
TESTES
X RADIATION