THE INFLUENCE OF OXYGEN ON THE RADIOSENSITIVITY OF MAMMALIAN TISSUES
The radiosensitivity of growing bone in the tail of weekold mice has been determined when the tissues were made anoxic by compression and when the animals were breathing partial pressures of oxygen ranging from half an atmosphere of air to three atmospheres of oxygen. When irradiation doses in the form of fast electrons, delivered in approximately one second, were used the tail reached minimum sensitivity following compression in four seconds. The changes in radiosensitivity found under these conditions are discussed in relation to the special anatomy and physiology of the sensitive cartilage cells concerned with the growth of the bones. The relation of these results with other work on mammalian tissue and cells is also discussed and some possible practical applications to radiotherapy are considered. (auth)
- Research Organization:
- St. Mary's Hospital Medical School; Hammersmith Hospital, London
- NSA Number:
- NSA-12-002631
- OSTI ID:
- 4349295
- Journal Information:
- Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn., Journal Name: Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn. Vol. Vol: 48; ISSN ACRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
QUANTITATIVE MEASUREMENTS OF OXYGEN TENSION IN NORMAL TISSUES AND IN THE TUMORS OF PATIENTS BEFORE AND AFTER RADIOTHERAPY
EFFECT OF HIGH PRESSURE OXYGEN ON RADIOSENSITIVITY OF EHRLICH'S TUMOR IN MICE AFTER "IMMUNOLOGICAL APPROXIMATION"