INVESTIGATION OF THE EFFECT OF X-RADIATION ON THE CARBOHYDRATE METABOLISM OF TUMOR CELLS

Journal Article · Mon Dec 31 23:00:00 EST 1956 · Strahlentherapie (West Germany)

OSTI ID:4346297

Maass, H; Rathgen, G H

After irradiating some inoculation tumors of the rat and of a human carcinoma with doses of from 10 to 25 kr, an unequivocai depression of the respiration and particularly of the aerobic and anaerobic glycolysis could be observed. The carbohydrate metabolism of the rat liver remained uninfluenced. By determination of some metabolite concentrations, the mechanism of the ray- induced inhibition of the glycolysis could be elucidated to a great extent. Accordingly it is probable that the point of attack of the ray effect must be searched for within the glycolysis chain at tbe step of the dehydrogenation of the triosephosphate. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-12-003502
• OSTI ID: 4346297
• Journal Information: Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 103; ISSN STRAA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

BIOCHEMISTRY
BIOLOGY AND MEDICINE
CARBOHYDRATES
CYTOLOGY
DECAY
ENERGY
HYDROGENATION
KAONS
LIVER
MAN
MEASURED VALUES
METABOLISM
NUCLEAR EMULSIONS
OXIDATION
PARTICLE TRACKS
PHOSPHATES
Q-VALUE
QUANTITATIVE ANALYSIS
QUANTITY RATIO
RADIATION EFFECTS
RATS
TAU MESONS
TUMORS
VELOCITY
X RADIATION