METABOLISM OF ESSENTIAL FATTY ACIDS. VII. CONVERSION OF $gamma$-LINOLENIC ACID TO ARACHIDONIC ACID
Journal Article
·
· Journal of Biological Chemistry (U.S.)
OSTI ID:4339471
Methyl gamma -linolenate-1-C/sup 14/ was fed to rats, and the fatty acids of depot and organ lipides of the rats were separated chromatographically and counted. The sole highly active fatty acid was arachidonic, which, after hydrogenation and degradation in three steps, was found to have 97% of the activity in carbon atom 3. These results support the hypothesis that gamma - linolenic acid is an intermediate in the conversion of linoleic acid to arachidonic acid. (auth)
- Research Organization:
- Univ. of California, Los Angeles
- NSA Number:
- NSA-12-004131
- OSTI ID:
- 4339471
- Journal Information:
- Journal of Biological Chemistry (U.S.), Journal Name: Journal of Biological Chemistry (U.S.) Vol. Vol: 229; ISSN JBCHA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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