Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases
- Oregon Health Sciences Univ., Portland, OR (United States); and others
We have cloned a novel human cDNA, INPPL1 (Gen-Bank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3{prime}-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples. 13 refs., 2 figs.
- OSTI ID:
- 433317
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 1 Vol. 29; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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