Methods for measurement of renal blood flow in man

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Semin. Nucl. Med., v. 4, no. 1, pp. 39-50

DOI:https://doi.org/10.1016/S0001-2998(74)80022-X· OSTI ID:4325652

Gruenfeld, J P; Sabto, J; Bankir, L; Funck-Brentano, J L

Methods currently available for measurement of renal blood flow with radionuclides in man include clearance-extraction ratio, indicator dilution, and inert-gas washout. Only the gas washout method, involving ¹³³Xe or ⁸⁵Kr, provides data on intrarenal distribution of blood flow; it also permits the measurement of renal blood flow of individual kidneys and may be used in oligoanuric patients. It necessitates selective catheterization of the renal artery and external counting. The gas washout technique represents to date the most satisfactory method of studying renal hemodynamics in man. However, several problems remain unresolved, among which are the assumption of instantaneous gas diffusion in any normal or pathological slate, the effects of the intraarterial bolus injection, the exact significance of the second component of the washout curve, and the value of data obtained by computer analysis of the curves.

• Research Organization: Hopital Necker, Paris
• Sponsoring Organization: USDOE
• NSA Number: NSA-29-021256
• OSTI ID: 4325652
• Journal Information: Semin. Nucl. Med., v. 4, no. 1, pp. 39-50, Journal Name: Semin. Nucl. Med., v. 4, no. 1, pp. 39-50; ISSN SMNMA
• Country of Publication: Country unknown/Code not available
• Language: English

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