PROPAGATION OF NON-IMPULSE EFFECTS ALONG A NERVE FROM A REGION EXPOSED TO X- IRRADIATION

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Biophysics (USSR) (English Translation)

OSTI ID:4325165

Kirzon, M V; Pshennikova, M G

Following irradiation of a small segment of frog nerve, the muscular responses to stimulation of the nerve at a point proximal to the irradiated part show that for a short period only a rise ia excitability takes place. This is followed by a progressive loss of conductivity in the irradiated segment. The rate of development of the block is dependent on radintinn dose. Stimulation in tbe nerve distal to the irradiated segment indicates that increased excitability develops. This process was irvestigated at distances of up to 25 mm from the limits of the irradiated segment. The rate with which muscular responses weakened was dependent on radiation dose and strength of stimuli applied in the distal nerve. Ideas are presented in support of the view that this weakening in muscular responses occurs as a result of a decline in the functional capacities of the neuro-muscular synapses and perhaps of the muscle itself. Changes in muscular response and the conclusions drawn from tbem regarding prolonged change in excitability in the distal part of the nerve, allow one to affirm that from the irradiated nerve trunk region nonimpulse effects are spread which become more pronounced despite cessation of irradiation and loss of conductivity in the irradiated part. (auth)

• Research Organization: Lomonosov State Univ., Moscow
• NSA Number: NSA-12-015238
• OSTI ID: 4325165
• Journal Information: Biophysics (USSR) (English Translation), Journal Name: Biophysics (USSR) (English Translation) Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMALS
BIOLOGY AND MEDICINE
DIFFUSION
DISTRIBUTION
FROGS
IRRADIATION
MUSCLES
NERVES
NERVOUS SYSTEM
PHYSIOLOGY
RADIATION DOSES
SENSITIVITY
VARIATIONS
X RADIATION