RADIOPROTECTIVE EFFICIENCY OF CYSTEAMINE DERIVATIVES (in Italian)
Journal Article
·
· Radiobiologica Latina
OSTI ID:4324614
The protective qualities of a series of cysteamine derivatives against ionizing radiations were investigated. In doses of the same degree of toxicity, cysteaminemonoacetic acid and glutamylcysteamine are just as effective as cysteamine. Gluconylcysteamine, even if quite active, is less so compared to cysteamine. Methioninamine has a sensitizing effect. These results are discussed in relation to the general formula proposed by Langedorff et al. for the radioprotective cysteamine derivatives and also in relation to the importance of the amino group in anti-x protection. (auth)
- Research Organization:
- Cancerologia sperimentale Ospedale Maggiore, Novara, Italy; Laboratori Ricerche Braco, Milan
- NSA Number:
- NSA-13-001936
- OSTI ID:
- 4324614
- Journal Information:
- Radiobiologica Latina, Journal Name: Radiobiologica Latina Vol. Vol: 1
- Country of Publication:
- Country unknown/Code not available
- Language:
- Italian
Similar Records
Thiazolidine prodrugs of cysteamine and cysteine as radioprotective agents
The Acute Toxic Effects of Cysteamine and Their Modification by X-irradiation
Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: Wr2721, cysteamine, diethyldithiocarbamate, and n-acetylcysteine
Journal Article
·
Tue Aug 01 00:00:00 EDT 1995
· Radiation Research
·
OSTI ID:121758
The Acute Toxic Effects of Cysteamine and Their Modification by X-irradiation
Journal Article
·
Sun Mar 31 23:00:00 EST 1963
· International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
·
OSTI ID:4666334
Comparative behavioral toxicity of four sulfhydryl radioprotective compounds in mice: Wr2721, cysteamine, diethyldithiocarbamate, and n-acetylcysteine
Technical Report
·
Thu Dec 31 23:00:00 EST 1987
·
OSTI ID:5646087