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THE EFFECTS OF IONIZING X-IRRADIATION ON THE ADULT AND IMMATURE MAMMALIAN BRAIN

Technical Report ·
OSTI ID:4310469
; ; ; ;
Data are presented from which it is conluded that the central nervous system is liable to severe damage from ionizing radiation. In general, the adult mammalian brain can withstand higher radiations without the deIn rats an apparent and significant radioresistence in 6 to 8 days of life. Although pathology is sometimes head irradiation of the new born. After large dosage irradiation to the heads of adult monkeys, the vital centers in the brain steam (hypothalamus and medulla) seem to be more radiosensitive than other regions in the nervous system. In our experiments this was recognized by neuronal, an neuroglial pathology and by the profound changes in vascular permeability observed in the hypothalamus and medulla following irradiation. A direct expalanation of the differences in radiosensitivity of the new born brain and the two week old brain cannot as yet be given. It is possible that there is a significant change in the water content of the nervous system during this period although we have not been able to uncover data along thesse lines to support this hypothesis. (auth)
Research Organization:
California. Univ., Los Angeles. School of Medicine
NSA Number:
NSA-12-014493
OSTI ID:
4310469
Report Number(s):
A/CONF.15/P/891
Country of Publication:
Country unknown/Code not available
Language:
English

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Related Subjects

AGE
ANIMALS
BIOLOGY AND MEDICINE
BLOOD CIRCULATION
CONFERENCE
DISTRIBUTION
HYPOTHALAMUS
MAMMALS
MEDICINE
MONKEYS
NERVOUS SYSTEM
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIOSENSITIVITY
RATS
VARIATIONS
WATER
X RADIATION