THE EFFECT OF IRRADIATION OF THE BODY ON THE VIRULENCE OF TYPHOID FEVER BACILLI

Journal Article · Sat Mar 01 04:00:00 EST 1958 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4309751

Chekatilo, G A

The study was carried out on the pathogenic properties of typhoid fever bacilli from the organism of irradiated (by 100, 200, and 300 r) and non- irradiated (control) guinea pigs. The animals were infected intracutaneously, after irradiation. The pathogenic properties of the microbes, isolated from the cutaneous foci, were examined by intraperitoneal inoculation of white mice with the dose of 15 and 30 million microbes. The total of 156 strains were examined and 762 mice were infected. lt was established that the mortality of mice infected with the bacterial cultures isolated from irradiated guinea pigs was higher than in mice infected with cultures isolated from non-irradiated mice (54.5% in the experimental group, as against 38% in the control group). Besides, it was revealed that the longer the microbes remained in the tissues of the macroorganism the greater became their virulence. This property was more pronounced in irradiated animals. Therefore, increase of the microbe virulence in the irradiated orgaaism is connected with the effect of irradiation which acts upon the microbes through the organism. (tr-auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-12-009601
• OSTI ID: 4309751
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 3, No. 2; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BACTERIA
BIOLOGY AND MEDICINE
BODY
GUINEA PIGS
INFECTIONS
MICE
RADIATION DOSES
RADIATION EFFECTS
X RADIATION