STUDY OF IODINE METABOLISM IN THE RAT BY AN ISOTOPIC EQUILIBRIUM METHOD: TOTAL IODINE RENEWAL SPEED OF THE ORGANISM UNDER VARIOUS PHYSIOLOGICAL CONDITIONS

Journal Article · Tue Jan 01 04:00:00 EST 1957 · Compt. rend. soc. biol.

OSTI ID:4303898

Morel, F; Simon, Cl

Male rats were fed a diet deficient in iodine, but they received in their drinking water a knownn amount of potassium iodide. At the beginning of the experiment, the iodide in the water was replaced by a daily injection of iodide marked with I(sup 131). The total radioactivity of the animal was measured externally each day. At the end of the experiment, the animals were killed and the amount of radioactivity in the thyroid and the skin was measured. In one series of experiments the rats also received a daily injection of thiouracile. The injection with the antithyroid sthrted 15 days after the beginning of the injections with radioiodine. The results showed that the quantity of iodine renewed each day increases with the amount of iodine in the diet. On the contrary, this quantity is not affected by the thiouracile. (J.S.R.)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-001061
• OSTI ID: 4303898
• Journal Information: Compt. rend. soc. biol., Journal Name: Compt. rend. soc. biol. Vol. Vol: 151
• Country of Publication: Country unknown/Code not available
• Language: French

Related Subjects

ADENOCARCINOMAS
BIOLOGY AND MEDICINE
CANCER
DIAGNOSIS
DRUGS
EFFICIENCY
EPITHELIOMA
IODINE 131
MAN
MEASURED VALUES
MEDICINE
METABOLISM
PHYSIOLOGY
POTASSIUM IODIDES
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIOACTIVITY
RADIOTHERAPY
RATS
SEX
SKIN
THIOURACIL
THYROID
TUMORS
WATER