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AN AFTEREFFECT OF IONIZING RADIATION ON A MUTANT OF ESCHERICHIA COLI

Journal Article · · Radiation Research
DOI:https://doi.org/10.2307/3570771· OSTI ID:4300796
A study- is being made of the effect of ionizing radiation on a mutant of Escherichia coli Monod that requires hemin for the synthesis of porphyrin- containing emymes. If growth occurs in the absence of hemin and the cells are consequently catalase and cytochrome-negative, a postirradiation inactivation is observed. This aftereffect is caused by the low concentration of hydrogen peroxide formed by irradiation in the medium surrounding the cells that survive the immediate effects of irradiation; it is not observed in unirradiated cells. This suggests that irradiation sensitizes these cells to hydrogen peroxide. (auth)
Research Organization:
Oak Ridge National Lab., Tenn.
Sponsoring Organization:
USDOE
NSA Number:
NSA-13-001084
OSTI ID:
4300796
Journal Information:
Radiation Research, Journal Name: Radiation Research Vol. Vol: 9
Country of Publication:
Country unknown/Code not available
Language:
English