MEDULLARY CELL SUSPENSION FOR RADIATION INDUCED BONE MARROW DAMAGE

Journal Article · Wed Jan 01 04:00:00 EST 1958 · Strahlentherapie (West Germany)

OSTI ID:4299387

Fliedner, T M

Inbred rats maintained at this institute were given 800 rep of radiation with 15 Mev electrons to the whole body. Immediately after irradiation the animals were injected intravenously with a suspension of bone marrow cells from unirradiated animals of the same strain. Compared to untreated control animals, there was a more rapid regeneration of the bone marrow beginning the third day after irradiation. Regeneration was more pronounced in the erythropoietic series; no significant acceleration of myelopoiesis resulted. The degree of hemorrhage noted on the third day after irradiation was less in the treated animals. The injected marrow did not affect the onset of marrow aplasia nor the circulatory changes seen within 24 hours of exposure.

• Research Organization: Univ. of Heidelberg
• NSA Number: NSA-12-012954
• OSTI ID: 4299387
• Journal Information: Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 106; ISSN STRAA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BLOOD CIRCULATION
BLOOD FORMATION
BLOOD VESSELS
BODY
BONE MARROW
ELECTRONS
ENERGY
ERYTHROCYTES
HEMORRHAGE
LEUCOCYTES
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RATS
REGENERATION
SUSPENSIONS
TRANSPLANTS
VARIATIONS